Biomedical & Health Informatics
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Calendar
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Date: January 16, 2006
Time: 12:45 - 2:00pm
Location: 214 Manning
Presenter: Brad Hemminger
Topic: Course overview and semester planning
Fall 2006
Date: November 20, 2006
Time: 3:30 - 4:30pm
Location: 214 Manning
Presenter: Meredith Pulley
Topic: Ontology merging tools
Documents:
Slides |
Summary
- P Lambrix, A Edberg. Evaluation of ontology merging tools in bioinformatics. Proceedings of the Pacific Symposium on Biocomputing-PSB03, 2003. Available free online
Date: October 30, 2006
Time: 3:30 - 4:30pm
Location: 214 Manning
Presenter: Laura Sheble
Topic: GIS and spatial analysis in epidemiology
Documents:
Slides |
Summary
- MJ Rytkonen. Not all maps are equal: GIS and spatial analysis in epidemiology. Int J Circumpolar Health. 2004 Mar;63(1):9-24. Available online.
Date: October 23, 2006
Time: 3:30 - 4:30pm
Location: 214 Manning
Presenter: Noel Fiser
Topic: A web application for research regulation compliance
Documents:
Slides |
Summary
- Pietrobon R, Shah A, Kuo P, Harker M, McCready M, Butler C, Martins H, Moorman CT, Jacobs DO. Duke Surgery Research Central: an open-source Web application for the improvement of compliance with research regulation. BMC Med Inform Decis Mak. 2006 Jul 27;6:32. PMID: 16872540. Available online
Date: October 16, 2006
Time: 3:30 - 4:30pm
Location: 214 Manning
Presenter: Meredith Pulley
Topic: Evaluating bioinformatics visualizations
Documents:
Slides |
Summary
- Saraiya, P.; North, C.; Duca, K. An insight-based methodology for evaluating bioinformatics visualizations. IEEE Transactions on Visualization and Computer Graphics, 11(4):443-456, July-Aug. 2005. Available online
Date: October 2, 2006
Time: 3:30 - 4:30pm
Location: 214 Manning
Presenter: Laura Sheble
Topic: Personal Health Information management
Documents:
Slides |
Summary
- Pratt, W. Unruh, K., Civan, A. and Skeels, M.M. (2006). Personal health information management. Communications of the ACM 49(1): 51-55. Available online.
Date: September 29, 2006
Time: 2:30 - 3:30pm
Location: 214 Manning
Presenter: Meredith Pulley
Topic: Mining biomedical literature
Documents:
Slides |
Summary
- B. de Bruijn, J. Martin. Getting to the (c)ore of knowledge: mining biomedical literature. International Journal of Medical Informatics, Volume 67, Issue 1-3, Pages 7-18. Available online
Date: September 25, 2006
Time: 3:30 - 4:30pm
Location: 214 Manning
Presenter: Noel Fiser
Topic: Agile methods in biomedical software development
Documents:
Slides |
Summary
- David W Kane, Moses M Hohman, Ethan G Cerami, Michael W McCormick, Karl F Kuhlmman and Jeff A Byrd. Agile methods in biomedical software development: a multi-site experience report. BMC Bioinformatics 2006, 7:273 (May 2006). Available online
Date: September 11, 2006
Time: 3:30 - 4:30pm
Location: 214 Manning
Presenter: Laura Sheble
Topic: Consumer and medical establishment contributions to public health surveillance
Documents:
Slides |
Summary
- Samaan G, Patel M, Olowokure B, Roces MC, Oshitani H; World Health Organization Outbreak Response Team. Rumor surveillance and avian influenza H5N1.Emerg Infect Dis. 2005 Mar;11(3):463-6. PMID: 15757567. Available free online
- Eysenbach G. SARS and population health technology. J Med Internet Res. 2003 Apr-Jun;5(2):e14. PMID: 12857670. Available free online
- Larkin, Marilynn. Blogs: new way to communicate about infectious diseases, The Lancet Infectious Diseases, Volume 5, Issue 12, , December 2005, Page 748. Available online.
Date: September 5, 2006
Time: 12:30 - 1:30pm
Location: 214 Manning
Presenter: Noel Fiser
Topic: The persistence of supplementary resources in biomedical publications
Documents:
Slides |
Summary
- Nicholas R Anderson, Peter Tarczy-Hornoch, Roger E Bumgarner. On the persistence of supplementary resources in biomedical publications. BMC Bioinformatics 2006, 7:260 Available free online
Date: August 29, 2006
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Brad Hemminger
Topic: Course overview and semester planning
Spring 2006
Date: April 19, 2006
Time: 5:15 - 6:15pm
Location: 304 Manning
Presenter: Brad Hemminger
Topic: Peer review exercise
- Allen, James, et al. Chester: Towards a personal medication advisor. Journal of Biomedical Informatics (Corrected Proof, available online 3 March 2006).
Available online.
Date: April 12, 2006
Time: 5:15 - 6:15pm
Location: 304 Manning
Presenter: Julia Kulla-Mader
Topic: Web databases for global infectious disease epidemiology
Documents:
Slides |
Summary
- Edberg SC. Global Infectious Diseases and Epidemiology Network (GIDEON): a world wide Web-based program for diagnosis and informatics in infectious diseases. Clinical Infectious Diseases 2005 Jan 1;40(1):123-126. PMID: 15614701.
Available online.
- Berger SA. GIDEON: a comprehensive Web-based resource for geographic medicine. Int'l Journal of Health Geographics 2005 Apr 22;4(1):10. PMID: 15847698.
Available online.
Date: April 5, 2006
Time: 5:15 - 6:30pm
Location: 304 Manning
Presenter: Noel Fiser
Topic: Real-time public health surveillance
Documents:
Slides |
Summary
- Tsui FC, Espino JU, Dato VM, Gesteland PH, Hutman J, Wagner MM. Technical description of RODS: a real-time public health surveillance system. J. American Medical Informatics Assoc. 2003 Sep-Oct;10(5):399-408. PMID: 12807803.
Available free online.
- Espino et al. Removing a barrier to computer-based outbreak and disease surveillance--the RODS Open Source Project. MMWR Morb Mortal Wkly Rep. 2004 Sep 24;53 Suppl:32-9. PMID: 15714624.
Available free online.
- Gesteland PH, Gardner RM, Tsui FC, Espino JU, Rolfs RT, James BC, Chapman WW, Moore AW, Wagner MM. Automated syndromic surveillance for the 2002 Winter Olympics. J. American Medical Informatics Assoc. 2003 Nov-Dec;10(6):547-54. PMID: 12925547.
Available free online.
Date: March 29, 2006
Time: 5:15 - 6:15pm
Location: 304 Manning
Presenter: Chris Maier
Topic: Infectious disease surveillance through emergency department complaints
Documents:
Slides |
Summary
- Brillman JC, Burr T, Forslund D, Joyce E, Picard R, Umland E. Modeling emergency department visit patterns for infectious disease complaints: results and application to disease surveillance. BMC Medical Informatics and Decision Making 2005 Mar 2;5(1):4. PMID: 15743535.
Available free online.
Date: March 22, 2006
Time: 5:15 - 6:15pm
Location: 304 Manning
Presenter: Julia Kulla-Mader
Topic: Users' activity modeling in electronic patient record design and assessment
Documents:
Slides |
Summary
- Beuscart-Zephir MC, Anceaux F, Crinquette V, Renard JM. Integrating users' activity modeling in the design and assessment of hospital electronic patient records: the example of anesthesia.
Int J Med Inform. 2001 Dec;64(2-3):157-71. PMID: 11734383.
Available online.
Date: March 1, 2006
Time: 5:15 - 6:30pm
Location: 304 Manning
Presenter: Noel Fiser
Topic: Cognitive modeling in healthcare interface design
Documents:
Slides |
Summary
- Johnson, C. & Turley J. (2006). The significance of cognitive modeling in building healthcare interfaces. International Journal of Medical Informatics, Volume 75, Issue 2, Pages 163-172. PMID: 16085454.
Available online.
Date: February 22, 2006
Time: 5:15 - 6:15pm
Location: 304 Manning
Presenter: Chris Maier
Topic: Predicting gene function from patterns of annotation
Documents:
Slides |
Summary
- King OD, Foulger RE, Dwight SS, White JV, Roth FP. Predicting gene function from patterns of annotation. Genome Research 2003 May;13(5):896-904. PMID: 12695322.
Available free online.
Date: February 15, 2006
Time: 5:15 - 6:30pm
Location: 304 Manning
Presenter: Noel Fiser
Topic: Protecting genomic data privacy
Documents:
Slides |
Summary
- Malin, Bradley and Latanya Sweeney. How (not) to protect genomic data privacy in a distributed network: using trail re-identification to evaluate and design anonymity protection systems. Journal of Biomedical Informatics 37(3), June 2004, Pp. 179-192. PMID: 15196482.
Available online.
Date: February 8, 2006
Time: 5:15 - 6:15pm
Location: 304 Manning
Presenter: Julia Kulla-Mader
Topic: Web usability for older adults
Documents:
Slides |
Summary
- Becker, S. A. 2004. A study of web usability for older adults seeking online health resources. ACM Trans. Comput.-Hum. Interact. 11, 4 (Dec. 2004), 387-406.
Available online.
Date: February 1, 2006
Time: 5:15 - 6:15pm
Location: 304 Manning
Presenter: Chris Maier
Topic: Semantic similarity measures in the Gene Ontology
Documents:
Slides |
Summary
- Lord PW, Stevens RD, Brass A, Goble CA. Investigating semantic similarity measures across the Gene Ontology: the relationship between sequence and annotation. Bioinformatics 2003 19: 1275-1283. PMID: 12835272.
Available online.
Date: January 17, 2006
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Brad Hemminger
Topic: Course overview and semester planning
Fall 2005
Date: December 6, 2005
Time: 12:30 - 1:30pm
Location: 328 Health Sciences Library
Presenter: Brad Hemminger
Topic: Information seeking behavior of scientists
Documents:
Slides |
Survey instrument
- Brad Hemminger will discuss preliminary results of an ongoing study of biomedical scientists' information seeking behavior. There is no journal article, but attendees should look at the slides and survey instrument linked above.
Date: November 29, 2005
Time: 12:30 - 1:30pm
Location: 328 Health Sciences Library
Presenter: Noel Fiser
Topic: Grid-based image archiving and analysis
Documents:
Slides |
Summary
- Hastings S, Oster S, Langella S, Kurc TM, Pan T, Catalyurek UV, Saltz JH. A grid-based image archival and analysis system. J Am Med Inform Assoc. 2005 May-Jun;12(3):286-95. PMID: 15684129.
Available online.
Date: November 15, 2005
Time: 12:30 - 1:30pm
Location: 328 Health Sciences Library
Presenter: John MacMullen
Topic: A method for determining prominent subdomains in medicine
Documents:
Slides
- Bernhardt PJ, Humphrey SM, Rindflesch TC. Determining Prominent Subdomains in Medicine. In Proceedings of the 2005 American Medical Informatics Association (AMIA) Annual Symposium, 46-50.
Available online - use Onyen & password to access.
Date: November 8, 2005
Time: 12:30 - 1:30pm
Location: 328 Health Sciences Library
Presenter: Noel Fiser
Topic: A knowledge-authoring environment for clinical end users
Documents:
Slides |
Summary
- Hulse NC, Rocha RA, Del Fiol G, Bradshaw RL, Hanna TP, Roemer LK. KAT: A flexible XML-based knowledge authoring environment. J Am Med Inform Assoc. 2005 Jul-Aug;12(4):418-30. PMID: 15802477.
Available online.
Date: October 18, 2005
Time: 12:30 - 1:30pm
Location: 328 Health Sciences Library
Presenter: John MacMullen
Topic: Measuring inter-annotator agreement in GO annotations
Documents:
Slides
- Camon EB, Barrell DG, Dimmer EC, Lee V, Magrane M, Maslen J, Binns D, Apweiler R. An evaluation of GO annotation retrieval for BioCreAtIvE and GOA. BMC Bioinformatics 2005; 6 Suppl 1:S17. PMID: 15960829.
Available online.
Date: October 11, 2005
Time: 12:30 - 1:30pm
Location: 328 Health Sciences Library
Presenter: Noel Fiser
Topic: A query language for biological networks
Documents:
Slides |
Summary
- Leser U. A query language for biological networks. Bioinformatics. 2005 Sep 1;21 Suppl 2:ii33-ii39. PMID: 16204121.
Available online
Date: October 4, 2005
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: John MacMullen
Topic: Assessing annotation consistency in the Gene Ontology
Documents:
Slides
- Dolan ME, Ni L, Camon E, Blake JA. A procedure for assessing GO annotation consistency. Bioinformatics. 2005 Jun 1;21 Suppl 1:i136-i143. PMID: 15961450
Available online
Date: September 27, 2005
Time: 12:30 - 1:30pm
Location: 328 Health Sciences Library
Presenter: John MacMullen
Topic: How well are protein structures annotated in secondary databases?
Documents:
Slides
- Rother K, Michalsky E, Leser U. How well are protein structures annotated in secondary databases? Proteins. 2005 Sep 1;60(4):571-6. PMID: 16021624.
Available online; see also the Protein Data Bank (PDB) site.
Date: September 20, 2005
Time: 12:30 - 1:30pm
Location: 328 Health Sciences Library
Presenter: Noel Fiser
Topic: A visualization method for high-dimensionality datasets
Documents:
Slides |
Summary
- Wong JW, Cartwright HM. Deterministic projection by growing cell structure networks for visualization of high-dimensionality datasets. J Biomedical Informatics 2005 Aug;38(4):322-30. PMID: 16084474.
Available online
Date: September 13, 2005
Time: 12:30 - 1:30pm
Location: 328 Health Sciences Library
Presenter: John MacMullen
Topic: The Mouse Genome Database: content and uses
Documents:
Slides
- Eppig, J.T., Bult, C.J., Kadin, J.A., Richardson, J.E., Blake, J.A., & the Mouse Genome Database Group. (2005). The Mouse
Genome Database (MGD): From genes to mice: A community resource for mouse biology. Nucleic Acids Research 33(1),
D471-D47.
Available online; see also Jackson Labs' Mouse Genome Informatics site.
Date: September 6, 2005
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: John MacMullen
Topic: Information problems in molecular biology and bioinformatics
Documents:
Slides
- MacMullen, W. John and Denn, Sheila O. (2005). Information problems in molecular biology and bioinformatics. Journal of the American Society for Information Science & Technology 56(5), 447-456.
Available online
Date: August 30, 2005
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: John MacMullen
Topic: Semester overview & planning
Spring 2005
Date: April 26, 2005
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Class members
Topic: Mock review of a journal article
- Yong-Chuan, T. and Leibel, R.L. (2002) Identifying functional relationships among human genes by systematic analysis of biological literature.
Available online
Date: April 19, 2005
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Patrick Herron
Topic: Enhancing disease-specific target selection with text mining
Documents:
Slides |
Summary
- Rubin DL, Thorn CF, Klein TE, Altman RB. A statistical approach to scanning the biomedical literature for pharmacogenetics knowledge. J Am Med Inform Assoc. 2005 Mar-Apr;12(2):121-9.
Available online
- Secondary article (a good framework for exploring the previous paper): Allen D. Roses, Daniel K. Burns, Stephanie Chissoe, Lefkos Middleton and Pamela St. Jean. Disease-specific target selection: a critical first step down the right road. Drug Discovery Today, Volume 10, Issue 3, 1 February 2005, Pages 177-189.
Available online
Date: April 12, 2005
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Class members
Topic: Mock research plan for system evaluation
Date: March 29, 2005
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Class members
Topic: Brainstorming session on discovery-support systems
Date: March 22, 2005
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Nancy Baker
Topic: Generating hypotheses by discovering implicit associations in the literature
Documents:
Slides |
Summary
- Marc Weeber, et al. (2003). Generating Hypotheses by Discovering Implicit Associations in the Literature: A Case Report of a Search for New Potential Therapeutic Uses for Thalidomide. Journal of the American Medical Informatics Association 10(3): 252?59.
Available online
Date: March 8, 2005
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Chris Maier
Topic: Evaluating methods for named entity recognition in biomedical texts
Documents:
Slides |
Summary
- Collier N, Takeuchi K. Comparison of character-level and part of speech features for name recognition in biomedical texts. Journal of Biomedical Informatics 2004 Dec;37(6):423-435. PMID: 15542016
Available online
Date: March 1, 2005
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Isaac Huffman
Topic: Classifying metabolic disorders using supervised machine learning
Documents:
Slides |
Summary
- Baumgartner, C. et al. Supervised machine learning techniques for the classification of metabolic disorders in newborns. Bioinformatics 2004 20: 2985-2996. PMID: 15180934.
Available online
Date: February 15, 2005
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Patrick Herron
Topic: Finding conceptual connections in MeSH
Documents:
Slides |
Summary
- Srinivasan P, Hristovski D. Distilling Conceptual Connections from MeSH Co-Occurrences. MEDINFO 2004; 808-12.
Available online (use amia/medinfo as usr/pwd)
Date: February 8, 2005
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Christopher Maier
Topic: NLP-based text-mining for biomedical relationship characterization
Documents:
Slides |
Summary
- Chen, H., & Sharp, B. M. Content-rich biological network constructed by mining pubmed abstracts. BMC Bioinformatics 5, 147 (October 2004).
Available online
Date: February 1, 2005
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Isaac Huffman
Topic: Structured evaluation methods for text mining
Documents:
Slides |
Summary
- Yeh, A.S., Hirschman, L., & Morgan, A.A. (2003). Evaluation of text data mining for database curation: lessons learned from the KDD Challenge Cup. Bioinformatics Vol. 19 Suppl. 1, pp. i331-i339.
Available online
Date: January 25, 2005
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Nancy Baker
Topic: Knowledge discovery via text mining
Documents:
Slides |
Summary
- Wren JD, et al. (2004). Knowledge discovery by automated identification and ranking of implicit relationships. Bioinformatics, 20(3):389-398.
Available online
Date: January 18, 2005
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Brad Hemminger
Topic: Introductory meeting for Spring 2005 semester
Fall 2004
Date: November 30, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Brad Hemminger
Topic: Comparison of search strategies in MEDLINE
- Jenuwine, Elizabeth S. & Floyd, Judith A. Comparison of Medical Subject Headings and text-word searches in MEDLINE to retrieve studies on sleep in healthy individuals. JMLA 2004 July; 92(3): 349-354.
Available online
Date: November 23, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Sayan Chakraborty
Topic: Health-seeking Behavior in India
Documents:
Slides |
Summary
Date: November 9, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Isaac Huffman
Topic: Primary care physicians and their information-seeking behaviour
Documents:
Slides |
Summary
- Nylenna, Magne; Gjerlow Aasland, Olaf (2000). Primary care physicians and their information-seeking behaviour. Scandinavian Journal of Primary Health Care 18(1), 9-13.
Available online
Date: November 2, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Bryan Howard
Topic: The changing array of sources for genetics information seeking
Documents:
Slides |
Summary
- Case, Donald O.; Johnson, J. David; Andrews, James E.; Allard, Suzanne L.; Kelly, Kimberly M. (2004). From two-step flow to the Internet: The changing array of sources for genetics information seeking. Journal of the American Society for Information Science and Technology, 55(8), 660-669.
Available online
Date: October 26, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Chris Maier
Topic: Disciplinary differences and undergraduates' information-seeking behavior
Documents:
Slides |
Summary
- Whitmire, Ethelene (2002). Disciplinary differences and undergraduates' information-seeking behavior. Journal of the American Society for Information Science and Technology 53(8), 631-638.
Available online
Date: October 19, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Nancy Baker
Topic: Differences in information seeking between physical and social scientists
Documents:
Slides |
Summary
- Ellis, David; Cox, Deborah; Hall, Katherine. (1993). A comparison of the information seeking patterns of researchers in the physical and social sciences. Journal of Documentation, 49(4), 356-369.
Available online, use your Onyen and password to access
Date: October 12, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: K.T.L. Vaughan / Brad Hemminger
Topic: Biomed scientists information behavior; UNC survey
Documents:
Slides
- Tenopir, Carol; King, Donald W.; Bush, Amy. (2004). Medical faculty's use of print and electronic journals: changes over time and in comparison with scientists. J Med Libr Assoc. 92(2): 233-241.
Available online
- Complete and comment on the 'Information Seeking Behavior of Science Researchers' survey Available online (use Onyen & password to access)
Date: October 5, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Sayan Chakraborty
Topic: Interface design
Documents:
Slides (in SVG format; viewer available here) |
Summary
- Bates, Marcia J. (1989). The Design of Browsing and Berrypicking Techniques for the Online Search Interface. Online Review, 13(5): 407-424.
Available online
Date: September 28, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Isaac Huffman
Topic: Evidence-based medicine
Documents:
Slides |
Summary
- Wickramasinghe, N., Sharma, S.K. & Reddy, H.P. (2005). Evidence-Based Medicine: A New Approach in the Practice of Medicine. In N. Wickramasinghe, J.N.D. Gupta & S. Sharma (eds.), Creating Knowledge-Based Healthcare Organizations (pp. 125-135), Hershey, PA: Idea Group Publishing.
Available online, use your Onyen and password to access
Date: September 21, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Bryan Howard
Topic: Information seeking behavior for complementary & alternative medicine
Documents:
Slides |
Summary
- Owen DJ, Fang ML. (2003). Information-seeking behavior in complementary and alternative medicine (CAM): an online survey of faculty at a health sciences campus. J Med Libr Assoc, 91(3): 311-321. PMCID: 164394
Available online
Date: September 14, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Christopher Maier
Topic: Information seeking behavior of scientists
Documents:
Slides |
Summary
-
Brown, C.M. (1999). Information seeking behavior of scientists in the electronic information age: astronomers, chemists, mathematicians, and physicists [at the University of Oklahoma]. Journal of the American Society for Information Science, 50(10), 929-943.
Available online
Date: September 7, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Nancy Baker
Topic: Grounded theory as an information-seeking research method
Documents:
Slides |
Summary
- Ellis, David (1993). Modeling the information-seeking patterns of academic researchers: A grounded theory approach. Library Quarterly 63(4), 469-486.
Available online, use your Onyen and password to access
Date: August 31, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: John MacMullen
Topic: Information problems in molecular biology and bioinformatics
Documents:
Slides
- MacMullen, W. John and Denn, Sheila O. (to appear). Information problems in molecular biology and bioinformatics. To appear in the forthcoming JASIS&T special issue on bioinformatics.
Available online, use your Onyen and password to access
Date: August 24, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Brad Hemminger
Topic: Introductory meeting for Fall 2004 semester
Spring 2004
Date: April 20, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Dihui Lu
Topic: Quering multiple bioinformatics information sources
- Buttler, David, et al. (2002). Quering multiple bioinformatics information sources: Can semantic web research help? ACM SIGMOD Record 31(4), 59-64.
Available online
Date: April 6, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Dihui Lu
Topic: BioMOBY
- Wilkinson, Mark D. & Links, Matthew (2002). BioMOBY: An open source biological web services proposal. Briefings In Bioinformatics, 3(4),331-341.
Available online
Date: March 30, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Lily Hsu
Topic: Extracting human protein interactions from MEDLINE
Documents:
Slides
- Nikolai Daraselia, et al. (2004). Extracting human protein interactions from MEDLINE using a full-sentence parser. Bioinformatics, 20(5), 604-611; DOI: 10.1093/bioinformatics/btg452
Available online
Date: March 23, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Patrick Herron
Topic: Open Source software in medical informatics -- why, how and what
Documents:
Slides |
Summary
-
Clement J. McDonald, et al. (2003). Open Source software
in medical informatics -- why, how and what. International Journal of
Medical Informatics, 69(2-3),175-184.
Available online
Date: March 16, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Nancy Baker
Topic: Structural location of disease-associated SNPs
Documents:
Slides
- Stitziel, Tseng, Pervouchine, Goddeau, Kasif, Liang (2003). Structural Location of Disease-associated Single-nucleotide Polymorphisms.
JMB 327, 1021-1030
Date: March 2, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: John MacMullen
Topic: Scientists' use of the biomedical literature
- reading available from presenter
Date: February 23, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Lily Hsu
Topic: Internet-based patient education
Documents:
Slides
- Nguyen, Huong Q; Virginia Carrieri-Kohlman; Sally H. Rankin; Robert
Slaughter; Michael S. Stulbarg. (2004). Internet-based patient education
and support interventions: a review of evaluation studies and directions for
future research. Computers in Biology and Medicine, 34(2), 92-112.
Available online
Date: February 10, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: K.T.L. Vaughan
Topic: Database resources for biomedical informatics
Date: February 3, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Patrick Herron
Topic: Designing metaschemas for the UMLS enriched semantic network
Documents:
Slides |
Summary
- Li Zhang, Yehoshua Perl, Michael Halper, and James Gellera (in press). Designing metaschemas for the UMLS enriched semantic network. Journal of Biomedical Informatics.
Available online
Date: January 20, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Nancy Baker
Topic: Recent trends in computer-aided drug discovery
Documents:
Slides
Date: January 13, 2004
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Brad Hemminger
Topic: First meeting of the semester
Fall 2003
Date: December 9, 2003
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Mao Ni
Topic: Graphical browsing of phylogenetic data
Documents:
Slides |
Summary
- Jakobsen, Ingrid B.; Saleeba, Jennifer A.; Poidinger, Michael; and Littlejohn, Timothy G. (2001). TreeGeneBrowser: phylogenetic data mining of gene sequences from public databases. Bioinformatics 17(6), 535-540.
Available online
Date: November 25, 2003
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Nancy Baker
Topic: Data mining in gene expression analysis
Documents:
Slides |
Summary
- Bassett, Jr, Douglas E.; Eisen, Michael B.; & Boguski, Mark S. (1999). Gene expression informatics ?it's all in your mine. Nature Genetics 21, Supplement, 51-55.
Available online
Date: November 18, 2003
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Trish Losi
Topic: Automatic discovery and classification of bioinformatics Web sources
Documents:
Slides |
Summary
- Rocco, Daniel & Critchlow, Terence (2003). Automatic discovery and classification of bioinformatics Web sources. Bioinformatics 19: 1927-1933.
Available online
Date: November 4, 2003
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Brad Hamminger
Topic: "Universal open archives; what are their flaws?"
Documents:
Slides
Date: October 28, 2003
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Kali Lewis
Topic: Perl programming at NCBI
Date: October 14, 2003
Time: 12:00 - 1:00pm
Location: Davis Library 2nd fl conference rm
Presenter: Brad Hemminger
Topic: Automated tools for scholarly communication
Date: October 07, 2003
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: John MacMullen
Topic: Representation of biomedical sublanguages using symbolic notation
Documents:
Slides |
Summary
- Harris, Zellig S. (2002). The structure of science information. Journal of Biomedical Informatics, 35, 215-221.
Available online
Date: September 30, 2003
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Mao Ni
Topic: Oracle's model for bioinformatics databases
Documents:
Slides |
Summary
- Banerjee, Sandeepan (2000). A database platform for bioinformatics. In VLDB 2000, Proceedings of 26th International Conference on Very Large Data Bases, 705-710.
Available online
Date: September 23, 2003
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: John Taylor
Topic: Inferring relationships from gene expression data
Documents:
Summary
- Kwon, Andrew Tae-Jun; Hoos, Holger H.; & Ng, Raymond (2003). Inference of transcriptional regulation relationships with gene expression data. In Proceedings of the 18th ACM Symposium on Applied Computing (SAC 2003).
Available online. See also the revised version in Bioinformatics.
Date: September 16, 2003
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Nancy Baker
Topic: Pathway databases
Documents:
Slides |
Summary
- Karp, P.D. (2001). Pathway Databases: A Case Study in Computational Symbolic Theories. Science, 293:2040-2044.
Available online
Date: September 9, 2003
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Trish Losi
Topic: Bioinformatics Training by Librarians and for Librarians
Documents:
Slides |
Summary
- Alpi, Kristine (2003). Bioinformatics training by librarians and for librarians: Developing the skills needed to support molecular biology and clinical genetics information instruction. Issues in Science and Technology Librarianship. Spring 2003.
Available online
Date: September 2, 2003
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: John MacMullen
Topic: Terminology-driven mining of biomedical literature
Documents:
Slides |
Summary
- Nenadic, G., Spasic, I., & Ananiadou, S. (2003). Terminology-driven mining
of biomedical literature. Bioinformatics 19(8), 938-943.
Available online
Date: August 26, 2003
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Brad Hemminger
Topic: Fall semester planning
Spring 2003
Date: April 22, 2003
Time: 12:30 - 1:30pm
Location: 208 Manning
Presenter: Trish Losi
Topic: The economics of e-publishing
- Willinsky, John (2003). Scholarly Associations and the Economic Viability of Open Access Publishing. Journal of Digital Information, 4.2.
Available online
Date: April 15, 2003
Time: 12:30 - 1:30pm
Location: 208 Manning
Presenter: Mary White
Topic: Integrating information specialists into practice settings
- Florance, V.; Giuse, N. & Ketchell, D. (2002). Information in context: Integrating information specialists into practice
settings. Journal of the Medical Library Association, 90(1), 49-58.
Available online
Date: April 8, 2003
Time: 12:30 - 1:30pm
Location: 208 Manning
Presenter: Dihui Lu
Topic: Biomedical ejournal archives and PubMed Central
Date: April 1, 2003
Time: 12:30 - 1:30pm
Location: 208 Manning
Presenter: John MacMullen
Topic: Theory and structure of MeSH
- Nelson, Stuart J.; Johnston, Douglas, Humphreys, Betsy L. (2001). Relationships in Medical Subject Headings. In Bean, Carol A. & Green, Rebecca (eds). Relationships in the Organization of Knowledge. New York: Kluwer Academic Publishers; 2001. p.171-184.
Available online
Date: March 25, 2003
Time: 12:30 - 1:30pm
Location: 208 Manning
Presenter: Mary White
Topic: Library-based bioinformatics services & resources
- Yarfitz, S. and Ketchell, D.S. (2000) A library-based bioinformatics services program. Bulletin of the Medical Library Association, 88(1), 36-48.
Available online
Date: March 18, 2003
Time: 12:30 - 1:30pm
Location: 208 Manning
Presenter: Trish Losi
Topic: The Open Archives Initiative (OAI)
- Lagoze, Carl and Van de Sompel, Herbert (2001). "The Open Archives Initiative:
Building a low-barrier interoperability framework." Proceedings of the
First ACM/IEEE-CS Joint Conference on Digital Libraries.
Available online
Date: March 4, 2003
Time: 12:30 - 1:30pm
Location: 208 Manning
Presenter: Brad Hemminger
Topic: NeoRef status report
Date: February 25, 2003
Time: 12:30 - 1:30pm
Location: 208 Manning
Presenter: Dihui Lu
Topic: Digital libraries and autonomous citation indexing
- Lawrence, Steve, Giles, C. Lee, & Bollacker, Kurt (1999). Digital Libraries and Autonomous Citation Indexing. IEEE Computer, 32(6), 67-71.
Available online
Date: February 18, 2003
Time:
Location:
Presenter:
Topic: No formal meeting. Registered students should add 5 documents and attributes to the NeoRef database.
Date: February 11, 2003
Time: 12:30 - 1:30pm
Location: 208 Manning
Presenter: Trish Losi
Topic: Preprint servers for scholarly publishing
Documents:
Slides
- Tomaiuolo, N.G., Packer, J.G. (2000). Preprint servers: Pushing the envelope of electronic scholarly publishing. Searcher 8(9), 53-61. Available online
Date: February 4, 2003
Time: 12:30 - 1:30pm
Location: 208 Manning
Presenter: John MacMullen
Topic: Automated meta-analysis: The METIS system
Documents:
Slides
Date: January 28, 2003
Time: 12:30 - 1:30pm
Location: 208 Manning
Presenter: Jian Yang
Topic: The Scholarly Ontologies (ScholOnto) project
Date: January 14, 2002
Time: 12:30 - 1:30pm
Location: 208 Manning
Presenter: Brad Hemminger
Topic: NeoRef
Documents:
Slides
Date: January 7, 2002
Time: 12:30 - 1:30pm
Location: 208 Manning
Presenter: Brad Hemminger
Topic: Global Knowledge Network
Fall 2002
Date: December 10, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: John MacMullen
Topic: Literature-based discovery in biomedicine
Documents:
Slides |
Summary
- Lindsay, R.K. & Gordon, M.D. (1999). Literature-based discovery by lexical statistics. Journal of the American Society for Information Science, 50(7), 574-587.
Available online
- (Optional) Gordon, M.D. & Lindsay, R.K. (1996). Toward discovery support systems: A replication, re-examination, and extension of Swanson's work on literature-based discovery of a connection between Raynaud's and fish oil. Journal of the American Society for Information Science, 47(2), 116-128.
Available online
Date: November 26, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Dihui Lu
Topic: User needs analysis for online bioinformatics resources for genome related research.
Date: November 12, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Trish Losi
Topic: Data mining: Linking diseases and genes
Documents:
Slides |
Summary
- Perez-Iratxeta, Carolina, Peer Bork & Miguel A. Andrade. (2002) Association of Genes to Genetically Inherited Diseases Using
Data Mining. Nature Genetics 31(3), 316-319.
Available online
- Mirnics, Karoly, et al. (2001) Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a
disease of the synapse. Trends in Neurosciences, 24(8), 479-486.
Available online
Date: November 5, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenters: Sheila Denn, John MacMullen
Topic: Information science applications to molecular biology. A preview of the Denn & MacMullen poster for the ASIS&T 2002 annual conference.
Documents:
Poster, abstract & references
Date: October 29, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Dihui Lu
Topic:
The Phytome database project for arabidopsis thaliana phylogeny information.
Date: October 22, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Trish Losi
Topic: Introduction to ontologies for bioinformatics
Documents:
Slides |
Summary
- Stevens, Robert, Carole A. Goble, and Sean Bechhofer (2002). "Ontology-based
Knowledge Representation for Bioinformatics." Briefings in Bioinformatics.
Available online
Also, at 3:30pm, Dr. John Michon of Duke University will be speaking to Jane Greenberg's metadata class about his work on the development of metadata schemas for opthamologic image databases. All are welcome to attend. Location: 307 Manning Hall
Date: October 15, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Brad Hemminger
Topic:
Mining the biomedical literature.
The biomedical literature may be the fastest-growing in the sciences.
What theories, methods and tools can Information and Library Sciences develop
to help researchers and practitioners organize, integrate, synthesize, and
extract knowledge from this sea of data and information?
Date: October 8, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: David Fargo, UNC Center for Bioinformatics
Topic: Use cases for bioinformatics -- we'll look at common questions biologists are using bioinformatics tools to answer.
Date: October 1, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Sheila Denn
Topic: User task analysis for bioinformatics
- Robert Stevens, Carole Goble, Patricia Baker, and Andy Brass (2001).
A classification of tasks in bioinformatics. Bioinformatics 17:180-188.
(Available online from UNC campus)
Date: September 24, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Trish Losi
Topic: Using the Gene Ontology to infer the function of uncharacterized proteins via a rule-based heuristic algorithm.
Documents:
Slides |
Summary
- Shug, Jonathan et. al. (2002). "Predicting Gene Ontology Functions from ProDom
and CDD Protein Domains." Genome Research 12(4),648-655.
(Available online from UNC campus)
Date: September 17, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: Dihui Lu
Topic: Databases for plant genomics and information science applications to plant comparative genetics.
- Gale, M.D. & Devos, K.M. (1998). Plant Comparative Genetics after 10 Years. Science 282: 656-659.
(Available online from UNC campus)
Date: September 10, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Presenter: John MacMullen
Topic: Discovery support systems for biomedical research and the fragmentation of knowledge in science.
Documents:
Slides |
Summary
- Swanson, Don R. and Smalheiser, Neil E. (1997). An interactive system for finding complementary literatures: a stimulus to scientific discovery. Artificial Intelligence 91(2), 183-202.
(Available online from UNC campus)
Date: September 3, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Topic: Phylogenetic analysis -- We'll look at standard ways to represent evolutionary relationships between organisms.
- Chapter 14, Phylogenetic Analysis, in Baxevanis & Ouellette's Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins, 2nd ed. A copy has been placed in the PAM box for this class (INLS 310-109) in the SILS Library. You can also read an earlier edition online (Chapter 9 in that edition), via the UNC Libraries web site. This works only within the UNC domain; if you're outside the domain accessing via the proxy, you must have a NetLibrary account.
Date: August 27, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Topic: Jian Yang will present on mouse genome databases and ontologies.
- The Gene Ontology Consortium (2001). Creating the Gene Ontology Resource: Design and Implementation. Genome Research 11:1425-1433.
(Available online)
- Ringwald, Martin, et al. (2001). The mouse gene expression database (GXD). Nucleic Acids Research 29(1), 98-101.
(Available online)
- Blake, Judith A., et al, (2002) The mouse genome database (MGD): the model organism database for the laboratory mouse. Nucleic Acids Research, 30(1):113-115.
(Available online)
Date: August 20, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Topic: First meeting of the semester. Introductions, overview, and discussion of potential readings for upcoming meetings.
Spring 2002
Date: July 23, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Topic: Todd Vision from the UNC Biology faculty will present an overview of his research and potential information science applications. Dr. Vision is also teaching Computational Genetics (BIO 162) in Fall 2002. The Vision Lab web site is here.
Date: July 16, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Topic: Discussion of mathematical challenges in genomics.
- Karp, Richard M. (2002). Mathematical Challenges from Genomics and Molecular Biology. Notices of the American Mathematical Society 49(5), 544-553.
(Online version available here)
Date: June 25, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Topic: Followup discussion of Claustres' article, and database models (federated vs centralized).
Date: June 11, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Topic: A community structure for normalization and integration of gene mutation databases
- Claustres, Mireille, et al. (2002). Time for a Unified System of Mutation Description and Reporting: A Review of Locus-Specific Mutation Databases. Genome Research 12: 680-688.
(Online version available here)
Date: May 28, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Topic: A continuation of our discussion of Ultra-Structure. One of the authors, Jeffrey Long, will answer questions and provide an overview of the applications for bioinformatics he has been working on.
Date: May 21, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Topic: Ultra-Structure and bioinformatics
- Long, Jeffrey G. and Denning, Dorothy E. (1995). Ultra-Structure: A Design Theory for Complex Systems and Processes. Communications of the ACM 38:1:103.
Date: March 19, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Topic: John MacMullen, UNC Bioinformatics Fellow, will describe an open metadata
framework for proteomics under development at UNC Chapel Hill.
Date: March 05, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Topic: Mary Parmelee (SILS) will present an overview of the
MIAME standard for microarray metadata.
Date: February 05, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Topic: Metabolites. Guest speakers: Jian Yang, Anne Bauers, Brad Hemminger. Join us for a discussion of the difficulties of
literature searching on a less than well defined domain. Our example is metabolites. Some are known, but there is no master list. Our goal: to
build a relational database capturing links between metabolites and other genomic related information. We began an investigation of this, and we'll talk about what we learned, and what work
remains to try to solve this problem.
Date: January 22, 2002
Time: 12:30 - 1:30pm
Location: 304 Manning
Topic: Basic issues in bioinformatics and the need for
information standards in the life sciences.
Fall 2001
Date: December 4, 2001
Time: 12:30 - 1:30pm
Location: 304 Manning
Topic: AMIA / ASIS&T recap. Those who attended either the American Medical Informatics Association (AMIA) annual meeting, or the American Society for Information Science & Technology (ASIS&T) meeting in Washington last month will talk about what they saw and learned about bio-/ medical informatics.
Date: November 20, 2001
Time: 12:30 - 1:30pm
Location: 304 Manning
Topic: Representatives from Incellico, Inc. will present their CELLĀ® suite of products, which provide an integrated graphical interface to multiple biological databases and nomenclature systems.
Date: November 13, 2001
Time: 12:30 - 1:30pm
Location: 304 Manning
Topic: Dr. David Fenstermacher, Director of the Center for Bioinformatics at UNC Chapel Hill, will present an overview of bioinformatics initiatives at UNC, and some of the driving problems in bioinformatics.
Date: October 30, 2001
Time: 12:30 - 1:30pm
Location: 304 Manning
Topic: John MacMullen, Bioinformatics Fellow at UNC Chapel Hill, will present an introduction to bioinformatics terminology, and lead a discussion of some of the research opportunities for information and library science.
Date: October 9, 2001
Time: 12:30 - 1:30pm
Location: 304 Manning
Topic: Students from Alex Tropsha's lab in the School of Pharmacy will present a complex, multi-database integration problem that they are experiencing with one of their experiments. We will brainstorm possible solutions.
Date: September 25, 2001
Time: 12:30 - 1:30pm
Location: 304 Manning
Topic: First meeting of the semester; introductions and overview of possible research topics.
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